2. Research Project 11

Research Project 11

Research project
Active research
Project period
2025 - 2029
Project owner
ANTHOGYR SAS (ANTHOGYR), France
Financier
EU - Horizon Europe, Marie Skłodowska-Curie Actions – Doctoral Networks, Grant Agreement No. 101226717
Area
Health and medicine
Science and Information Technology
Topic
Research

Short description

Evaluation of biomimetic geometries and nanostructured titanium surfaces to secure the peri-implant tissues from infectious complications.

Project Description

Short description: DC11 will develop and evaluate nanostructured implant surfaces designed to reduce bacterial adhesion and promote soft tissue healing. The project includes in vitro testing of biofilm formation and tissue compatibility, and a clinical study comparing customized, anatomically shaped devices with traditional designs. These efforts aim to improve implant success rates and manage infections effectively amid rising antimicrobial resistance.

Learn more about this position at EURAWESS

Objectives

The PhD student will work on a PhD project aiming to prepare and characterize innovative surfaces treatments on dental implants and evaluate the clinical performance of biomimetic and personalized macroscopic designs for soft-tissue healing. The project will be conducted using in vitro models in collaboration with leading universities (University of Gothenburg and University of Oslo). These approaches will be ultimately evaluated through clinical trial in a very close collaboration with Hospices Civils de Lyon, France, where the PhD candidate will be registered and co-supervised by senior researchers from University of Lyon.

Research activities include:

  • Characterization of nanostructured surfaces
  • Simulating biofilm model/host interactions via a flow cell co-culture system with bacteria and fibroblasts
  • Assessing the effectiveness of customized, anatomically shaped devices using in vitro and/or animal models
  • Develop and conduct an interventional study protocol on patients to compare the most effective nanostructured surface with a polished reference surface at individual implant sites.

Training and mobility:

  • Research secondments at SHIELD partner institutions:
    • Hospices Civils de Lyon (France)
    • University of Gothenburg (Sweden)
    • University of Oslo (Norway)

Participation in specialized training workshops and international conferences.

Expected Results


More information about the Doctoral positions at this EURAXESS's link

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